Web  Lecture - McEwen - page 2 - slides # 7-12
Go to Slides #1-6, #7-12, #13-18, #19-24, #25-30, #31-36 , #37-41
 
"Sex, Stress and the Hippocampus: Receptors, Intracellular Mechanisms and Synaptic Plasticity"
Bruce S. McEwen, PhD

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Slide 7: We are interested in the hippocampus because it contains adrenal steriod receptors.
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Slide 8: Glutamate is another important player in the hippocampal drama.
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Slide 9: Parts of the entorhinal cortex/ mossy fiber / schaeffer collateral circuit  undergo structural remodeling as a result of repeated stress.
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Slide 10: In parts of this tri-synpatic circuit, activation of adrenal steriod receptors can potentiate and suppress LTP and LTD.
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Slide 11: Adult neurogenesis in the hippocampus.
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Slide 12: A number of factors increase  stem cell division in dentate gyrus. Stress can suppress generation of new cells.
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